Stanford Physician Advocate

How Vaccine Hesitancy is Reviving Deadly Childhood Diseases: Measles, first identified as a virus in the early 20th century, caused widespread illness and death before the introduction of a vaccine in 1963. The vaccine, developed from a live virus strain isolated from an infected child, revolutionized public health. By the 1970s and 1980s, widespread vaccination programs—particularly the MMR (measles, mumps, rubella) vaccine—became standard in childhood immunization schedules.

The impact was undeniable. Annual measles cases in the U.S. dropped from 500,000 before the vaccine to fewer than 100 by the early 2000s. The World Health Organization (WHO) spearheaded global initiatives to eradicate measles, emphasizing the life-saving power of vaccines.

The Rising Threat of Vaccine Hesitancy

Despite these remarkable achievements, vaccine hesitancy has become a growing concern. Communities with low vaccination rates—such as certain areas in Texas—have witnessed renewed measles outbreaks. This hesitancy undermines herd immunity, leaving entire populations vulnerable. Although measles was declared eliminated in the U.S. in 2000, international travel and anti-vaccine sentiments have fueled a troubling resurgence.

A Physician’s Perspective: Witnessing the Shift

As a family physician who practiced in the Seattle area for 42 years, I have witnessed firsthand how vaccines transformed pediatric care. In the 1970s, I frequently admitted children with infectious diseases such as meningitis, Haemophilus influenzae, and whooping cough. However, with the advent of widespread immunization, I began to see fewer critically ill children. Reviving Deadly Childhood Diseases

Other Deadly Diseases Prevented by Vaccines

Vaccines have also drastically reduced the prevalence of other life-threatening diseases, including:

  • Diphtheria: A severe illness that can cause heart complications.
  • Measles: Declared eliminated by the CDC in 1978, but capable of causing birth defects if contracted by pregnant women.
  • Mumps: Added to the MMR vaccine in 1971, preventing widespread infection.
  • Polio: Targeted for global eradication by Rotary International in 1985.
  • Whooping Cough: A highly contagious disease significantly reduced through immunization.

In 1900, 20% of children died before age five, mostly from preventable infectious diseases. Thanks to vaccines, this devastating statistic has become a relic of the past.

Herd Immunity: Why High Vaccination Rates Matter

For vaccines to effectively protect communities, at least 80% of the population must be immune to prevent the spread of disease. Unfortunately, vaccine hesitancy threatens this critical threshold. As fewer people vaccinate, herd immunity deteriorates, placing entire populations at risk.

The Paradox of Vaccine Success

Vaccines, in many ways, have become victims of their own success. Their effectiveness has eradicated diseases so thoroughly that many people today have never witnessed the devastating effects of these illnesses. This lack of firsthand experience has fueled the perception that the risks associated with these diseases are minimal. However, if too many people underestimate the threat, herd immunity disappears—and the risk of outbreaks grows.

A Call to Action for Physicians and Public Health Leaders

To combat vaccine hesitancy, physicians and health care leaders must actively engage with communities, dispel misinformation, and emphasize the proven safety and efficacy of vaccines. We must reinforce the message that immunization not only protects individuals but also safeguards entire communities from preventable diseases.

About the Author

Dr. Robert Bettis, a family physician with over four decades of experience, has dedicated his career to patient care, medical research, and education. As the founder of a thriving clinic with over 100 staff members, Dr. Bettis has delivered exceptional health care for more than 42 years. His research, published in JAMA, Clinical Therapeutics, and The Journal of Antimicrobial Chemotherapy, has advanced knowledge in antibiotic efficacy, respiratory infections, and chronic disease management. Dr. Bettis has also served as a part-time faculty member at the University of Washington’s Department of Family Medicine, leaving a lasting legacy in medical education and clinical excellence.


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